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Im quoting several paragraphs here because she is explaining this much better than I can (Since Ive never really watched the much of the show): As with many of the series final episodes, the decision to kill off Betty with lung cancer was rather on-the-nose

To compare those values to the values we found in our studies, conservative assumptions (respiratory minute volume-40L

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Simply put: if you inhale deep and fast, the vapor will go directly to your lungs and has a big chance of triggering a cough